Schizophrenia
Biologic treatments:
- its treatments primarily comprise medications that target the abnormalities in the brain
- conventional antipsychotics
- binds to dopamine receptors, but do not stimulate them, blocks them
- atypical antipsychotics
- aim: less side effects
- only blocks dopamine temporarily, then return to normal
- antidepressant medications
- electroconvulsive therapy
- seizure in patients reduced symptoms
- usually 3-15 treatments
Gene Therapy treatments:
- researchers have identified a gene regulator that could help faulty brain functions
- miRNA (microRNA)= noncoding RNA molecules that can regulate activity of hundreds of genes
- unclear how genetic variations impact miRNA 137
- abnormal levels of miRNA-137 impact cellular function
- in reprogrammed neurons from human fibroblasts of diseased patients microRNA-137 was
Increased
- down regulating miRNA 137 improves synaptic transmissions in neurons
- drug abuse or stress can alter miRNA 137 levels
- avoiding an unhealthy lifestyle or drugs in a critical phase of brain development might prevent disease onset
Antibodies treatments:
-Antibody treatments are highly unlikely to be productive due to the fact that in some cases schizophrenia may be partially caused by antibodies in some cases. This is due to the fact that antibodies
Drug Delivery System:
- Drug delivery refers to approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect.
- The way the drug is dissolved into the body doesn’t matter but how frequent the drug must be taken might need to be changed based off how intense the schizophrenia affects the person.
Vaccine treatment:
- new drug is called paliperidone palmitate. It's an injectable form of the second-generation, or "atypical," antipsychotic medication Invega.
- one shot a month
- most common side effects were weight gain and stomach flu
Biologic treatments:
- its treatments primarily comprise medications that target the abnormalities in the brain
- conventional antipsychotics
- binds to dopamine receptors, but do not stimulate them, blocks them
- atypical antipsychotics
- aim: less side effects
- only blocks dopamine temporarily, then return to normal
- antidepressant medications
- electroconvulsive therapy
- seizure in patients reduced symptoms
- usually 3-15 treatments
Gene Therapy treatments:
- researchers have identified a gene regulator that could help faulty brain functions
- miRNA (microRNA)= noncoding RNA molecules that can regulate activity of hundreds of genes
- unclear how genetic variations impact miRNA 137
- abnormal levels of miRNA-137 impact cellular function
- in reprogrammed neurons from human fibroblasts of diseased patients microRNA-137 was
Increased
- down regulating miRNA 137 improves synaptic transmissions in neurons
- drug abuse or stress can alter miRNA 137 levels
- avoiding an unhealthy lifestyle or drugs in a critical phase of brain development might prevent disease onset
Antibodies treatments:
-Antibody treatments are highly unlikely to be productive due to the fact that in some cases schizophrenia may be partially caused by antibodies in some cases. This is due to the fact that antibodies
Drug Delivery System:
- Drug delivery refers to approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect.
- The way the drug is dissolved into the body doesn’t matter but how frequent the drug must be taken might need to be changed based off how intense the schizophrenia affects the person.
Vaccine treatment:
- new drug is called paliperidone palmitate. It's an injectable form of the second-generation, or "atypical," antipsychotic medication Invega.
- one shot a month
- most common side effects were weight gain and stomach flu